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分類清單
王祖興
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王祖興 教授

Dr. Tsu-Shing Wang


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Tel:(04)2473-0022 ext 11811;12313

Fax:(04)2324-8187

tsushing@csmu.edu.tw

學經歷
學歷:
  • 國立清華大學輻射生物學博士
經歷:
  • 中山醫學大學教授及醫科院院長 2011.8~迄今
  • 中山醫學大學教授及系主任 2010.8~2011.7
  • 中山醫學大學副教授~2010.7
  • 中山醫學大學助理教授~2005.7
  • 中山醫學大學教務處綜合服務組組長
  • 法國居禮研究院博士後研究

研究方向及計畫
  • 98年度:
    香煙萃物誘發ICAM-1基因增加表現之分子機制及防治研究 (國科會 98-2320-B-019-MY3)
  • 96年度:
    生地黃、葛根、黨蔘、北耆及天花粉熱水提取物在糖尿病合併症保健功效之探勘 (國科會 96-2320-B-040-023)
  • 95年度:
    香煙萃物在人類臍靜脈內皮細胞造成膜上E-selection及ICAM-1表達增加之分子機制探討 (國科會 NSC 95-2314-B-040-034)
  • 94年度:
    亞砷酸鈉及過氧化氫造成人類臍靜脈內皮細胞蛋白質羰基化:模式蛋白質及蛋白質體學探討 (國科會 NSC 94-2314-B-040-028)
  • 93年度:
    台農二號山藥水萃取物保肝活性及可能分子機制之探討 (國科會 DOH93-TD-F-113-019)
  • 91年度:
    山藥水萃物銅離子螯合活性有效分子確認及對銅離子代謝異常相關疾病保健功效之評估
  • 89年度:
    山藥抽取物質抗氧化活性及其對哺乳動物細胞氧化性傷害可能之保護角色

專長及教授課程
  • 細胞生物學
  • 普通生物學
  • 核酸轉錄調節機制
研究著作
  1. 期刊論文
    1. Yu, A.L., Lu, C.Y., Wang, T.S., Tsai, C.W., Liu, K.L., Cheng ,Y.P., Chang, H.C., Lii, C.K., Chen, H.W. 2010. Induction of heme oxygenase 1 and inhibition of tumor necrosis factor alpha-induced intercellular adhesion molecule expression by andrographolide in EA.hy926 cells. J Agric Food Chem 58(13):7641-7648. (SCI)

    2. Lii,C.K., Lin, A.H., Lee, S.L., Chen, H.W., Wang T.S. 2010. Oxidative modifications of proteins by sodium arsenite in human umbilical vein endothelial cells. Environ Toxicol (in press). (SCI)

    3. Tsai, C.W., Lin, A.H., Wang T.S., Liu, K.L, Chen, H.W. Lii, C.K. 2010. Methionine restriction up-regulates the expression of the pi class of glutathione S-transferase partially via the extracellular signal-regulated kinase-activator protein-1 signaling pathway initiated by glutathione depletion. Mol Nutr Food Res 54:1-10. (SCI)

    4. Lin, C.C., Su, T.H., Wang, T.S. 2009. Protein carbonylation in THP-1 cells induced by cigarette smoke extract via a copper-cat aly zed pathway. Chem Res Toxicol 22(7): 1232-1238. (SCI)

    5. Kuo, C.F., Hou, M.H., Wang, T.S., Chyau, C.C., Chen, Y.T. 2009. Enhanced antioxidant activity of Monascus pilosus fermented products by addition of ginger to the medium. Food Chem 116: 915-922. (SCI)

    6. Chen, H.W., Lii, C.K., Ku, H.J., Wang, T.S. 2009. Cigarette smoke extract induces expression of cell adhesion molecules in HUVEC via actin filament reorganization. Environ Mol Mutage 50(2): 96-104. (SCI).

    7. Wang, T.S., Lii, C.K., Chang, J.Y., Kuo, C.I, Chen, H.P. 2007. Anti-Fenton reaction activity of three taxa of water yam (Dioscorea alata L.). Internat J Food Sci Technol 42( 9):1107-1113. (SCI)

    8. Lee, Y.C., Yang, V.C., Wang, T.S. 2007. Use of RAPD to detect sodium arsenite-induced DNA da ma ge in hu ma n lymphoblastoid cells. Toxicology 239(1-2):108-115. (SCI)

    9. Kuo, C. F., Wang, T.S., Yang, P.L., Jao, Y.C. Lin, W.Y. 2006. Antioxidant Activity of Liquid-State Fermentation Products of Monascus pilosus Grown in Garlic-Containing Medium. J Food Sci 71(6): S456-S460. (SCI)

    10. Chen, Y.T., Hsieh, C.Y., Lii, C.K., Liu, S.Y., Wang, T.S. 2006. Inhibitory effects of water yam (dioscorea alata L.) on glucose-induced protein glycation: a comparative study with four Chinese medicines for treating diabetes. Nutrt Sci J 31(4):137-145.

    11. Chen, H.W., Chien, M.L., Chaung, Y.H., Lii, C.K., Wang, T.S. (2004). Extracts from cigarette smoke induce DNA da ma ge and cell adhesion molecule expression through different pathways. Chem Biol Interact 150(3):233-241. (SCI)

    12. Wang, T.S., Liang, S.J., Lii, C.K., Liu, S.Y. (2004). Protective effect of water yam (Dioscorea alata L.) extract on the copper-driven Fenton reaction and X-ray induced DNA da ma ge in vitro. Phytother Res 18(4):325-328. (SCI)
  2. 研討會論文
    • Lii, C.K., Lin, A.H., Lee, S.L., Chen, H.W., Wang, T.S. 2009. Oxidative modicifcation of proteins by sodium arsenite in hu ma n umbilical vwein endothelial cells. Abstract of 19th International congress of nutrition, Tailand.

    • Huang, Y.C., Chen, Y.F., Wang, T.S. 2009. Protective effects of traditional Chinese medicinal herbs against DNA da ma ge induced by oxidants in ECV304 cells. Abstract of 24th Joint Annual Conference of Biomedicals Science, R.O.C.

    • Roan, H.Y., Chen, Y.F., Hunag, Y.C., Wang, T.S. 2008. Antioxidant and antiglycation properties of aqueous extracts from traditional Chinese herbs in vitro. Abstract of 23th Joint Annual Conference of Biomedicals Science, R.O.C.

    • Lee, Y.C., Yang, V.C., Wang T.S. 2007. Detection of sodium arsenite-induced DNA da ma ge in lymphoblastoid cells. Abstract of 11th Internation Congress of Toxicology, .

    • 李叔蓮、王祖興、李宗貴.2004.亞砷酸鈉誘發人類臍靜脈內皮細胞蛋白質氧化硝基化之探討:二維電泳分析. 中華民國營養學會第三十屆年會暨學術研討會。

    • 莊玉涵、王祖興、陳暉雯.2004.香煙萃取物對人類臍靜脈內皮細胞的氧畫傷害.中華民國營養學會第三十屆年會暨學術研討會。
  3. 專書及專書論文
    • 王祖興(2006) 生物學實驗 (ISBN: 978-986-412-334-6), 高立圖書出版, pp105.
    • Wang, T.S., 1996. Cellular and molecular mechanisms of arsenite toxicity. Ph.D. Thesis.