吳亭萱 助理教授
Dr. Ting-Hsuan Wu
Tel:(04)36097722 ext 11802
tingwu@csmu.edu.tw
學歷:
- 中山醫學大學醫學研究所博士
經歷:
- 中山醫學大學助理教授
專長及教授課程:
- 發育生物學
- 胚胎毒理
- 精準醫學
- 食品毒理
期刊論文:
- Cheng, P.L., Hsiao, T.H., Chen, C.H., Hung, M.N., Jhan, P.P., Lee, L.W., Wu, T.S., Tsai, J.R., Teng, C.L. (2023, Feb). Chemoresistance in acute myeloid leukemia: An alternative single cell RNA sequencing approach. ‐ Hematological Oncology, 1-11. (SCI, 99/246, Oncology).
- Tsai, J.F., Wu, T.S., Yu, F.Y., Liu, B.H. (2023, Jan). Neurotoxicity of mycotoxin citrinin: Novel evidence in developing zebrafish and underlying mechanisms in human neuron cells. Food and Chemical Toxicology, 171, 113543. (SCI, 17/310 food science). nstc 107-2320-B-002-023-MY3.
- Hu, RH., Wu, C.T., Wu, T.S., Yu, F.Y., Ko, J.L., Lue, K.H., Liu, Y.F. (2022, Jan). Systematic Characterization of the Group 2 House Dust Mite Allergen in Dermatophagoides microceras. Frontiers in Cellular and Infection Microbiology, 11:793559. (SCI, 33/136, MICROBIOLOGY).
- Cheng, Y.C., Wu, T.S., Huang, Y.T., Chang, Y., Yang, J.J., Yu, F.Y., Liu, B.H (2021, Jun). Aflatoxin B1 interferes with embryonic liver development: Involvement of p53 signaling and apoptosis in zebrafish. Toxicology, 458, 152844. (SCI, 22/94, Toxicology). MOST 107-2320-B-002-023-MY3. Cheng YC and Wu TS contributed equally to this work. 本人為共同第一作者.
- Wu, T.S., Lin, Y.T., Huang, Y.T., Yu, F.Y., Liu, B.H. (2020, Mar). Ochratoxin A triggered intracerebral hemorrhage in embryonic zebrafish: Involvement of microRNA-731 and prolactin receptor. Chemosphere, 242,125143. (SCI, 33/279, ENVIRONMENTAL SCIENCES). MOST 104-2320-B-002- 037-MY3. 本人為第一作者.
- Wu, T.S., Cheng Y.C., Chen P.J., Huang, Y.T., Yu, F.Y., Liu, B.H. (2019, Feb). Exposure to aflatoxin B1 interferes with locomotion and neural development in zebrafish embryos and larvae. Chemosphere, 217, 906-913. (SCI). MOST 104-2320-B-002-037-MY3. 本人為第一作者.
- Huang, Y.T, Wu, T.S., Lu, C.C.,Yu, F. Y.,Liu, B.H. (2018, Apr). Aristolochic acid I interferes with the expression of BLCAP tumor suppressor gene in human cells. Toxicology Letters, 291:129-137. (SCI, 28/94 Toxicology). MOST 104-2320-B-002-037-MY3. 本人為共同第一作者. Huang YT and Wu TS contributed equally to this work.
- Wu, T. S., Lin, Y. T., Huang, Y.T., Cheng, Y. C., Yu, F. Y., and Liu, B.H. (2017, Dec). Disruption of liver development and coagulation pathway by ochratoxin A in embryonic zebrafish. Toxicology and Applied Pharmacology, 340:1-8. (SCI, 19/94 Toxicology). 本人為第一作者.
- Wu, T.S., Yang, J.J., Wang, Y.W., Yu, F.Y., and Liu, B.H. (2016, Jan). Mycotoxin ochratoxin A disrupts renal development via a miR-731/prolactin receptor axis in zebrafish. Toxicology Research, 5, 519-529. (SCI, 66/94 Toxicology). MOST 104-2320-B-002-037-MY3. 本人為第一作者.
- Wu, T. S., Yang, J. J., Yu, F. Y., and Liu, B. H. (2013, Sep). Cardiotoxicity of mycotoxin citrinin and involvement of microRNA-138 in zebrafish embryos. Toxicological Sciences, 136(2), 402-412. (SCI, 11/92, Toxicology). NSC 101-2313-B-002-071-MY3. 本人為第一作者.
- Wu, T. S., Yang, J. J., Yu, F. Y., and Liu, B. H. (2012, Jul). Evaluation of nephrotoxic effects of mycotoxins, citrinin and patulin, on zebrafish (Danio rerio) embryos. Food and Chemistry Toxicology, 50, 4398-4404. (SCI, 8/123, Food science and technology). NSC 98-2313-B-040-004-MY3. 本人為第一作者.
- Liu, M. C, Lin, T. H., Wu, T. S., Lu, C. C., Liu, B. H.* (2011, Feb). Aristolochic acid I suppressed iNOS gene expression and NF-κB activation in stimulated macrophage cells. Toxicology Letter, 202期,p.93-p.99. (SCI, 21/88, Toxicology). NSC 97-2313-B-040-004-MY3.
- Yu, F. Y., Wu, T. S., Chen, T. W., Liu, B. H* (2011, Feb). Aristolochic acid I induced oxidative DNA damage associated with glutathione depletion and ERK1/2 activation in human cells. Toxicology in vitro, 25期,p.810-p.816. (SCI, 29/88, Toxicology). NSC 96-2313-B-040-004-MY3. 本人為第一作者.
- Chang, C. H., Yu, F. Y., Wu, T. S., Wang, L. T., Liu, B. H*. (2011). Mycotoxin Citrinin induced cell cycle G2/M arrest and numerical chromosomal aberration associated with disruption of microtubule formation in human cells. Toxicological Sciences, 119期,p.84-p.92. (SCI, 11/88 Toxicology). NSC 97-2313-B-040-004-MY3.
- Wu, T. S., Liao, Y. C., Chang, C. H., Liu, B. H.* (2008, Nov). Mechanism of patulin-induced apoptosis in human leukemia cell. Toxicology letter, 183期, p.105-p.111. (SCI). NSC 95-2313-B-040-003-MY2. 本人為第一作者.
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Liu, B. H., Wu, T. S., Yu, F. Y., Su, C. C. (2007). Induction of oxidative stress response by the mycotoxinpatulin in mammalian cells. Toxicological Sciences, 95期,p. 340-p.347. (SCI). NSC 94-2313-B-040-001.
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Liu, B. H*., Wu, T. S., Wang, C. H. (2006). Mycotoxin patulin activates p38 and JNK signaling pathways in human embryonic kidney cells. Toxicological Sciences, 89期, p.423-p.430. (SCI). NSC 93-2313-B-040-001. 本人為共同第一作者.
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Wu, T. S., Yu, F. Y., Su, M. C., Kan, C. C., Liu, B. H*. (2005, Feb). Activation of ERK mitogen-activated protein kinase by mycotoxin Patulin in human cells. Toxicology and Applied Pharmacology, 207期, p.103-p.111. (SCI). NSC 92-2313-B-040-003. 本人為第一作者.
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Liu, B. H., Wu T. S., Su, M. C., Chung, C. P., Yu, F. Y*. (2005). Evaluation of Citrinin Occurrence and Cytotoxicity in Monascus Fermentation Products. Journal of Agricultural and Food Chemistry, 53期,p.170-p.175. (SCI).
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Yu, F. Y., Liu, B. H., Wu, T. S., Chi, T. F., Su, M. C. (2004, Aug). Development of a sensitive enzyme-linked immunosorbent assay for the determination of domoic acid in shellfish. Journal of Agricultural and Food Chemistry, 52期,p.5334-p.5339. (SCI). NSC 90-2313-B-040-005.
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Liu, B. H., Yu, F. Y., Wu, T. S., Li, S. Y., Su, M. C., Wang, M. C. and Shih, S. M. (2003, May). Evaluation of genetic risk and oxidative damage in mammalian cells exposed to mycotoxins, patulin and citrinin. Toxicology and Applied Pharmacology, 191期, p.255-p.263. (SCI). NSC 90-2316-B-040-001.